Fig. 2.

A Constructed vaccine candidates by linker and quality assessment. a Tertiary structural constructs of ~ 1–12 P′ small peptides in each connect to ~ 1–7(L) linkers (GPGPG and EAAAK) of the vaccine model were determined by (ORION) peptide fold recognition. b The structural quality estimation of vaccine model was DOPE Energy: − 181.9, and Z-score of Energy: − 0.961, and c overall vaccine model quality has Z-score: − 1.99 determined by ProSA and arranged all residues show knowledge-based energy plot. B Energy minimizations of SARS-nCoV-2 proteins construct peptides. Energy graph of SARS-nCoV-2-designed peptide-based vaccine region range (~ 1–12 P′) and simulation of RMSD graph