Fig. 4.

MHC class I and II T cell allele and epitope modeling and docking. The T cell receptor consists of four binding domains in different colors (Cα: green; Cβ: violet; Vα: green; and Vβ: violet). MHC class II and I consist of four binding domains in different colors (α1, α2, α3, and β2). Vaccine candidates of SARS-nCoV-2 antigenic peptides consist of a ~ 1–12 P′ binding complex between pMHC and TCR. MHC–TCR epitope complex minimized structure at the end of simulations t = 0 and t = 200 ns antigenic peptide, as shown in between the middle of complex (yellow)