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. 2021 Jan 29;14:315–327. doi: 10.2147/IDR.S294149

Table 4.

Antimicrobial Susceptibilities of E. Anophelis Isolates Determined by the Broth Microdilution Method

Antimicrobial Agents Breakpoint (μg/mL) MIC (μg/mL) Susceptibility (%)
Susceptible Resistant Range 50% 90% Susceptible Intermediate Resistant
Piperacillin ≤16 ≥128 16–128 32 64 17.9 74.4 7.7
Piperacillin-TZB ≤16 ≥128 4–64 16 32 71.8 28.2 0
Ceftazidime ≤8 ≥32 128 to >256 >256 >256 0 0 100
Ceftazidime-CLA ≤8 ≥32 32 to >256 >256 >256 0 0 100
Ceftazidime-AVI ≤8 ≥16 64 to >256 >256 >256 0 0 100
Cefepime ≤8 ≥32 32 to >256 >256 >256 0 0 100
Cefepime-CLA ≤8 ≥32 32 to >256 256 >256 0 0 100
Aztreonam ≤8 ≥32 >256 >256 >256 0 0 100
Aztreonam-AVI ≤8 ≥16 >256 >256 >256 0 0 100
Imipenem ≤4 ≥16 16 to >256 64 128 0 0 100
Meropenem ≤4 ≥16 16 to >256 64 256 0 0 100
Levofloxacin ≤2 ≥8 0.5–32 8 16 38.5 2.6 60.0
Ciprofloxacin ≤1 ≥4 0.5 to >256 64 256 30.8 2.6 66.6
Minocycline ≤4 ≥16 0.25–1 0.5 1 100 0 0
Tigecycline ≤2 ≥8 2–8 4 4 10.3 82.1 7.6
Fosfomycin ≤32 >32 >256 >256 >256 0 0 100
Colistin ≤2 >2 >256 >256 >256 0 0 100
Vancomycin ≤2 ≥16 8–32 16 32 0 20.5 79.5
Rifampicin ≤1 ≥4 1–32 2 16 20.5 33.3 46.2

Abbreviations: MIC, minimum inhibitory concentration; TZB, tazobactam at a fixed concentration of 4 μg/mL; AVI, avibactam at a fixed concentration of 4 μg/mL; CLA, clavulanic acid at a fixed concentration of 2 μg/mL.