TABLE 2.
Demographic and clinical characteristics of osteoarthritis patients: discovery and testing groups
| Knee OA (discovery group; n = 46) | Knee OA (testing group; n = 45) | p‐Value | Hip OA (testing group; n = 23) | p‐Value | |
|---|---|---|---|---|---|
| Age (years), mean, SD | 65.3 ± 7.41 | 65.78 ± 5.6 | .75 | 59.5 ± 7.41 | .007* |
| Sex (female), n, % | 30; 65.2% | 38; 84% | .035* | 8; 40% | .008* |
| BMI (kg/m2), mean, SD | 30 ± 4.3 | 30.87 ± 5.54 | .41 | 28.8 ± 3.36 | .08 |
| Education, n, % | .15 | .76 | |||
| Primary education | 34; 73.9% | 38; 84.4% | 14; 70% | ||
| Secondary education | 8; 17.4% | 6; 13.3% | 4; 20% | ||
| Postsecondary education | 4; 8.7% | 1; 2.2% | 2; 10% | ||
| Smoking, n, % | 4; 8.7% | 3; 6.7% | .71 | 2; 8.7% | 1.0 |
| Habitation, n, % | .59 | .52 | |||
| Alone | 10; 21.7% | 7; 15.6% | 3; 13% | ||
| Cohabitation | 36; 78.3% | 38; 84.4% | 20; 90% | ||
| Marital status, n, % | .19 | .57 | |||
| Married | 30; 65.2% | 35; 77.8% | 16; 70% | ||
| Never married | 3; 6.5% | 2; 4.4% | 2; 8.7% | ||
| Divorced | 4; 8.7% | 3; 6.7% | 2; 8.7% | ||
| Widowed | 9; 19.6% | 5; 11.1% | 3; 13% | ||
| NRS, mean, SD | 6.48 ± 1.42 | 6.8 ± 1.93 | .37 | 6.2 ± 1.59 | .21 |
| DN4, mean, SD | 2.7 ± 2.26 | 2.9 ± 2.15 | .55 | 1.82 ± 1.49 | .025* |
| HADS_D, mean, SD | 7.9 ± 3.93 | 6.7 ± 4.33 | .15 | 5.8 ± 4.45 | .46 |
| HADS_A, mean, SD | 8.6 ± 4.07 | 9 ± 5.71 | .71 | 6.5 ± 4.19 | .07 |
| HOOS_S, mean, SD | 60.5 ± 19.31 | 61.9 ± 21.8 | .74 | 50 ± 16.02 | .023* |
| HOOS_P, mean, SD | 63.6 ± 16.52 | 64.2 ± 16.43 | .87 | 55 ± 17.75 | .063 |
| HOOS_ADL, mean, SD | 61.4 ± 15.84 | 64.4 ± 17.54 | .38 | 57.9 ± 18.3 | .15 |
| HOOS_SR, mean, SD | 91.5 ± 17.63 | 91.6 ± 15.75 | .97 | 83.15 ± 19 | .054 |
| HOOS_QL, mean, SD | 78.6 ± 16.37 | 80 ± 17.46 | .68 | 70.6 ± 20.4 | .051 |
| PCS, mean, SD | 19.1 ± 12.33 | 23.3 ± 15.75 | .15 | 18.1 ± 11.01 | .16 |
| Pain duration (years), mean, SD | 6.8 ± 5.45 | 8.5 ± 6.44 | .61 | 5.03 ± 4.2 | .021* |
| Radiographic KLS, n, % | .33 | <.001* | |||
| Grade 1 | 1; 2.2% | — | — | ||
| Grade 2 | 12; 26.1% | 9; 20% | — | ||
| Grade 3 | 21; 45.7% | 22; 48.9% | 5; 21.7% | ||
| Grade 4 | 12; 26.1% | 14; 31.1% | 18; 72.2% | ||
| STUG, mean, SD | 13.12 ± 3.93 | 13.9 ± 4.8 | .41 | 14.26 ± 4.46 | .77 |
| 6MWT, mean, SD | 257.8 ± 75.5 | 272.4 ± 68.93 | .33 | 271.7 ± 99 | .9 |
*p<.05.
Abbreviations: 6MWT, 6‐min walking test; ADL, activities of daily living; ANOVA, analysis of variable; BMI, body mass index; DN4, Douleur Neuropathique en 4 questions; HADS, Hospital anxiety and Depression Scale; HOA, hip OA; HOOS, Hip Injury and Osteoarthritis Outcome Score; KL, Kellgren–Lawrence scale; KOA, knee OA; KOOS, Knee injury and Osteoarthritis Outcome Score; NRS, numeric pain rating; OA, osteoarthritis; PCS, Pain Catastrophizing Scale; QoL, quality of life; SR, sports and recreation; STUG, stand up and go test.
Note: p‐Values represent statistical tests between KOA discovery groups and the holdout testing samples; KOA testing sample showed a significantly higher number of females, no other differences were captured; HOA group was significantly different regarding age, gender, DN4 scale, pain duration, and radiographic severity (KLS). ANOVA and t tests were performed for continuous data. Chi‐square tests were performed for categorical data.