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. Author manuscript; available in PMC: 2022 Feb 15.
Published in final edited form as: Bioorg Med Chem. 2021 Jan 8;32:116000. doi: 10.1016/j.bmc.2021.116000

Figure 2. Infectivity of CD4-negative Cf2Th-CCR5 cells by CD4-dependent HIV-1ADA.

Figure 2.

CCf2Th-CCR5 cells were infected with CD4-dependent HIV-1ADA in the presence of NBD-14273 and NBD-556, which was used as a control. The Relative virus infectivity indicates the ratio of the amount of infection detected in the presence and absence of the compounds. Three independent experiments were performed in triplicate, and the graph is representative of one experiment. The toxicity of the compounds against these cells was evaluated to calculate the CC50 values: for NBD-556, the CC50 was > 60, and for NBD-14273, it was 31.2±1.4. All the values represent the mean ± standard deviation.