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. 2021 Jan 26;21(3):236. doi: 10.3892/ol.2021.12497

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — LH inhibits OSCC cell proliferation in vitro. (A) Chemical structure of LH. (B) HSC-3, HSC-4, UM1 and UM2 OSCC cell lines were incubated with LH at the indicated concentrations for 24 h, and cell proliferation was measured using a CCK-8 assay. (C) HSC-3 cells were incubated with LH at the indicated concentrations for 24 and 48 h, and cell proliferation was measured using a CCK-8 assay. IC50 value of LH-treated OSCC cells was calculated with GraphPad Prism 7 software. OSCC, oral squamous cell carcinoma; LH, lycorine hydrochloride; CCK-8, Cell Counting kit-8.