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. 2021 Feb 3;19:17. doi: 10.1186/s12958-021-00705-4

Table 3.

Histological analysis

Control Melatonin p-value
Immature Follicles 7.20 ± 3.23 6.00 ± 2.55 0.66
Mature Follicles * 3.01 ± 0.91 8.75 ± 2.02 0.04
Corpora Lutea 7.86 ± 1.71 5.22 ± 1.05 0.34
Collagen type I* 5.75 ± 0.52 8.52 ± 1.04 0.03
Collagen type III* 3.53 ± 0.28 1.49 ± 0.15 < 0.001
Collagen type I and III ratio 1.62 5.71
Blood vessels 20.13 ± 3.66 18.63 ± 3.65 0.99

Ovarian follicle density, collagen, and blood vessels (mean ± standard deviation) comparing the use of melatonin added to the cryopreservation medium or not, in rat ovarian slide, autologous cryopreserved grafts after the 30th day of transplantation (n = 10 in each group); *p < 0.05 t-test.