Table 1.
Clinical and histological characteristic of hepatitis C virus patients before treatment (n = 38)
Parameters | |
Age (yr) | 40.9 ± 14.6 |
Males, n (%) | 20 (53) |
ALT (U/L) | 54 (30) |
TBil (μmol/L) | 11.5 (6.7) |
Albumin (g/L) | 45.7 ± 3.5 |
Platelets (× 103 μL) | 173.6 ± 63.6 |
INR | 1.00 (0.10) |
HCV RNA (log IU/L) | 6.24 ± 0.79 |
LSM, kPa | 6.6 (3.6) |
HCV genotype | |
1 | 23 (60) |
2 | 3 (8) |
3 | 12 (32) |
Treatment, n (%) | |
SOF + RBV | 17 (45) |
DCV + ASV | 14 (37) |
GZR + EBR | 7 (18) |
HAI score, n (%) | |
0-3 | 6 (16) |
4-6 | 12 (32) |
7-9 | 9 (24) |
≥ 10 | 11 (29) |
Ishak score, n (%) | |
F0-2 | 8 (21) |
F3-4 | 17 (45) |
F5-6 | 13 (34) |
ALT: Alanine aminotransferase; TBil: Total bilirubin; INR: International normalized ratio; HCV: Hepatitis C virus; LSM: Liver stiffness measurement; SOF + RBV: Sofosbuvir + ribavirin; DCV + ASV: Daclatasvir + asunaprevir; GZR + EBR: Grazoprevir + elbasvir; HAI: Histology activity index.