Fig 2.
Histopathological features of biopsied purpuric skin lesions. A, The epidermis and underlying follicular epithelium exhibited necrosis, resulting in a subepidermal vesiculation (original magnification, ×100). B, Fibrin thrombi and erythrocytes were seen plugging the superficial dermal blood vessels (original magnification, ×200). C, The eccrine coils also exhibited necrosis (original magnification, ×200). D, SARS-CoV-2 RNA in-situ hybridization was negative with the inset showing positive staining in pulmonary control tissue (original magnification, ×200; inset - original magnification, ×400).