Table 1.
Demographic and clinical characteristics at ICU admission, and SLED parameters.
| Variable | Pt. 1 | Pt. 2 | Pt. 3 | Pt. 4 |
|---|---|---|---|---|
| Age, yr | 49 | 63 | 54 | 47 |
| Male | Y | Y | Y | Y |
| Comorbidities, | ||||
| Arterial hypertension | N | Y | Y | N |
| Diabetes mellitus | Y | Y | Y | N |
| CKD | N | N | N | N |
| APACHE II score | 36 | 31 | 22 | 30 |
| SOFA score | 16 | 14 | 12 | 16 |
| Invasive mechanical ventilation | Y | Y | Y | Y |
| Serum creatinine, mg/dL | 2 | 0.6 | 4.2 | 1.5 |
| BUN, mg/dl | 24 | 18 | 80 | 26 |
| Platelet count, x 103/mL | 118 | 284 | 248 | 448 |
| INR | 1.33 | 1.34 | 1.28 | 1.32 |
| aPTT ratio | 1.02 | 1.11 | 1.22 | 1.02 |
| ICU stay, days | 33 | 40 | 48 | 75 |
| Duration of mechanical ventilation, days | 30 | 38 | 48 | 70 |
| Death in the ICU | N | N | N | N |
| Death during hospital stay | N | N | N | N |
| Prescribed SLED sessions, n/patient | 23 | 16 | 2 | 8 |
| SLED duration, hours (median, IQ range) | 12 (9.5–12.5) | 8 (8–12) | 10 (9–11) | 10 (8.7–12) |
| Causes of SLED interruption | ||||
| Programmed end of treatment (%) | 18 (78.3) | 14 (87.5) | 2 (100) | 6 (75) |
| Circuit clotting (%) | 2 (8.7) | 1 (6.2) | - | - |
| CVC malfunctioning (%) | 2 (8.7) | 1 (6.2) | - | 1 (12.5) |
| Other clinical reasons (%) | 1 (4.3) | - | - | 1 (12.5) |
| Duration of KRT, days | 29 | 27 | 4 | 8 |
ICU, Intensive Care Unit; SLED, Sustained Low-Efficiency Dialysis; Pt, Patient; CKD, Chronic Kidney Disease; APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment; BUN, Blood Urea Nitrogen; CVC, Central Venous Catheter; KRT, Kidney Replacement Therapy. Y, Yes; N, No.