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. 2020 Dec 7;5(54):eabe0240. doi: 10.1126/sciimmunol.abe0240

Fig. 8. Correlations between anti-SARS-CoV-2 spike RBD antibody responses, spike pseudovirus neutralization activity, and viral RNA in individual deceased patients.

Fig. 8

Individual patient plots show the development of RBD IgM, IgG, and IgA antibody responses (upper panels for each patient) and RBD-ACE2 blocking antibodies (lower panels for each patient) for all available plasma sample time points. Orange shading indicates time admitted in the hospital, while red shading represents the timeframe patients were treated in the ICU. The time of death is indicated in each plot with a star. Representative plots for individuals with no (Group 1), up to 25% (Group 2) and over 25% (Group 3) RBD-ACE2 blocking activity are shown here. Plots for the remaining deceased patients are shown in fig. S11B. The time point and Ct value for the diagnostic NP swab SARS-CoV-2 rRT PCR is shown as a turquoise triangle in the lower panel.