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. 2021 Jan 5;22(2):e50927. doi: 10.15252/embr.202050927

Figure 8. Stromal Rb1 controls epithelial proliferation and embryo invasion in cooperation with epithelial Rb1 .

Figure 8

  1. RB was efficiently deleted in the uterine epithelium of uterine epithelium‐specific conditional knockout mice (Rb1 eKO mice). Scale bar = 100 μm. Rb1 eKO mice, Rb1loxP/loxPLtfCre /+ mice; Rb1 eControl mice (littermate controls of Rb1 eKO mice), Rb1loxP/loxP mice; le, luminal epithelium; s, stroma.
  2. Number of new‐born pups was comparable between Rb1 eKO and eControl dams (mean ± SEM, Student’s t‐test; n = 10 different dams for each group).
  3. The expression patterns of Ki67 on day 4 in uterine epithelium were comparable between Rb1 eKO and Rb1 eControl mice. Scale bar = 100 μm; le, luminal epithelium; s, stroma.