Figure 8.

Comparison of the substrate binding sites between FigC and SbnH.A, ribbon diagram showing an alignment of FigC (pink and green as in Fig. 7) with SbnH (pdb 6knk) (purple). Structures were aligned in Pymol using the align command to an RMSD of 2.7 Å over 3211 atoms. N-citryl-2,3-diaminoethane (NcDE) bound to SbnH is displayed as large spheres. The PLP bound to FigC is not shown. B, alignment of the active site of FigC overlaid with a docked ligand (PLP-N-citrylputrescine [PLP-Ncp]) (green) with SbnH (purple). PLP-Ncp is shown in turquoise as sticks, and PLP-NcDE is shown in purple as ball and sticks. The SbnH structures is displayed in thinner sticks, and the font sized used to label the SbnH residues is smaller than for FigC for clarity.