Table 2. New-onset metabolic features and cardiovascular events (with n, % and age-sex adjusted risk ratios) after 7-years (2014), among control, NAFLD and MAFLD.

Outcomes in 2014	Controls N* = 255	NAFLD N* = 708	Adjusted RR (95% confidence intervals) for NAFLD vs controls, p value	MAFLD N* = 735	Adjusted RR (95% confidence intervals) for MAFLD vs controls, p value
Incident general obesity	9/254 (3.5%)	53/215 (24.6%)	7.7 (3.8–15.4) <0.001	57/213 (26.8%)	8.3 (4.1–16.6) <0.001
Incident central obesity	39/246 (15.9%)	37/109 (33.9%)	2.6 (1.8–3.8) <0.001	44/101 (43.6%)	3.3 (2.3–4.7) <0.001
Incident DM	31/243 (12.8%)	203/503 (40.4%)	3.1 (2.2–4.4) <0.001	216/523 (41.3%)	3.2 (2.3–4.5) <0.001
Incident HTN	36/218 (16.5%)	109/232 (33.7%)	2.1 (1.4–2.8) <0.001	111/326 (34.0%)	2.1 (1.5–2.9) <0.001
Incident TG	68/231 (29.4%)	145/361 (40.2%)	1.3 (1.1–1.7) 0.026	153/372 (41.1%)	1.4 (1.1–1.7) 0.010
Incident low HDL	68/208 (32.7%)	246/461 (53.4%)	1.5 (1.2–1.7) <0.001	250/487 (51.3%)	1.5 (1.2–1.8) <0.001
CVD non-fatal and fatal events	4/253 (1.6%)	36/665 (5.4%)	3.7 (1.3–10.3) 0.013	43/692 (6.2%)	4.2 (1.5–11.5) <0.006

N*—Number in the original 2007 cohort irrespective of presence or absence of baseline condition. Individuals with existing condition at baseline were excluded in the calculation of risk ratios.