Table 4. Clinical characteristics of patients with biallelic or potentially biallelic NRAP variants.
| Patient | Age | Gender | Phenotype | LVEDD(mm)/EF% | Age at onset | Htx | Died | Other |
|---|---|---|---|---|---|---|---|---|
| 1 | 19 | F | DCM | NA | <19 | Yes, at age of 19 | ||
| 2 | 36 | F | DCM | 71/10-15% | NA | 36 | ||
| 3 | 31 | M | DCM | 70/13% | 28 | Mild LGE | ||
| 4 | 57 | M | DCM | NA | 56 | Maximum treatment for heart failure | ||
| 5 | 4 | F | DCM | 58/20% | 4 | LVAD | ||
| 6 | 59 | F | DCM | 63/34% | 46 | |||
| 7 | 59 | M | DCM | NA/30% | NA | LBBB | ||
| 8 | 43 | M | DCM | NA | 22 | Yes, at age 43 | ||
| 9 | 53 | F | DCM | NA | NA | History of cardiac arrest | ||
| 10 | 48 | M | DCM/HF | NA | NA | |||
| 11 | 2 | M | DCM | NA | NA | 2 |
Age means age at last follow-up. Abbreviations: DCM, Dilated cardiomyopathy; EF, Ejection fraction; F, Female; HF, Heart failure; Htx, Heart transplantation; LBBB, Left bundle branch block; LGE, Late gadolinium enhancement at cardiac MRI; LVEDD, Left ventricular end-diastolic diameter in mm; M, Male; NA, Not available or not known.