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. 2021 Feb 3;16(2):e0245653. doi: 10.1371/journal.pone.0245653

Fig 1. Pten knockout increases collagen fiber formation.

Fig 1

(A) Second harmonic generation (SHG) and picrosirius red staining surrounding ducts in murine mammary tissue sections. SHG images are shown above their corresponding picrosirius red images. (B) Quantification of the number of collagen fibers in SHG images, shown as mean+SD with individual values plotted, n = 32 ducts imaged across 7 WT mice, 23 ducts imaged across 5 Pten-/- mice. (C) Histogram of collagen fiber length in SHG images. (D) Histogram of collagen fiber width in SHG images. ***p<0.001.