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. 2021 Feb 3;16(2):e0245653. doi: 10.1371/journal.pone.0245653

Fig 6. SPARC expression induced by Pten knockout promotes collagen and fibronectin fiber formation.

Fig 6

(A) Immunofluorescence images of cells incubated with fluorescently labeled collagen and fibronectin for 24 hours, then fixed and stained for actin and nuclei. (B) Quantification of the area of each image covered by collagen fibers normalized to number of nuclei in each image. (C) Quantification of the area of each image covered by fibronectin fibers normalized to number of nuclei in each image. n = 3+SD. *p<0.05 relative to Pten-/-. **p<0.01 relative to Pten-/-.