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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: J Psychosom Res. 2020 Dec 25;141:110342. doi: 10.1016/j.jpsychores.2020.110342

Figure 1. Mediation analysis linking mental stress-induced myocardial ischemia and worse executive function over time through peripheral vasoconstriction.

Figure 1.

Total and indirect effects of sPAT on the association between mental stress-induced ischemia and worsening executive function. Indirect effect= 0.35*0.17. This pathway accounted for 18.2% of the total effect (indirect effect/(indirect effect + direct effect) x100).

Model adjusted for demographics (age, sex, race, and education), clinical variables (body mass index, hypertension, hyperlipidemia, diabetes mellitus, smoking history, prior myocardial infarction, and heart failure) and medication use (aspirin, statin, angiotensin-converting enzyme inhibitor, and beta-blockers).