Table 1.
Baseline characteristics of study participants
| Parameter | All participants | sUmod Q1 | sUmod Q2 | sUmod Q3 | sUmod Q4 | P-value |
|---|---|---|---|---|---|---|
| n | 1075 | 269 | 269 | 268 | 269 | – |
| sUmod (ng/mL), mean ± SD | 152.5 (110.0–207.7) | 84.8 (64.9–96.6) | 129.8 (120.7–141.0) | 177.1 (166.3–190.9) | 248.2 (224.9–281.8) | – |
| Sex (female), n (%) | 528 (49) | 108 (40) | 116 (43) | 135 (50) | 169 (63) | <0.001a |
| Age (years), mean ± SD | 70.2 ± 5.5 | 71.8 ± 5.7 | 70.8 ± 5.6 | 69.7 ± 5.3 | 68.8 ± 4.8 | <0.001b |
| BMI (kg/m2), mean ± SD | 28.7 ± 4.5 | 29.7 ± 4.8 | 29.2 ± 4.7 | 28.6 ± 4.0 | 27.4 ± 4.1 | <0.001b |
| Arterial hypertension, n (%) | 669 (62) | 202 (75) | 184 (68) | 152 (57) | 131 (49) | <0.001a |
| Type 2 diabetes, n (%) | 213 (20) | 82 (30) | 59 (22) | 48 (18) | 24 (9) | <0.001a |
| HbA1c (mmol/mol) | 37.7 (35.5–41.0) | 38.8 (36.6–43.2) | 38.8 (36.6–41.0) | 37.7 (35.5–41.0) | 37.7 (34.4–39.9) | <0.001c |
| eGFR (mL/min/1.73 m²), mean ± SD | 76.4 ± 15.7 | 67.9 ± 18.4 | 74.4 ± 14.0 | 80.2 ± 12.8 | 83.2 ± 11.5 | <0.001a |
| Urinary albumin: creatinine ratio (mg/g) | 8.4 (4.7–17.6) | 12.4 (6.4–32.4) | 7.9 (4.4–15.9) | 7.5 (4.5–13.7) | 6.8 (4.3–12.7) | <0.001c |
| Urinary albumin: creatinine ratio ≥30 mg/g, n (%) | 167 (16) | 72 (27) | 42 (16) | 28 (10) | 25 (9) | 0.003a |
a
Chi-square test.
b
Kruskal–Wallis test.
c
Analysis of variance test.
Value presented as median (first quartile–third quartile) unless stated otherwise.