Table 1.

List of studies and trials comparing early with late start of dialysis treatment in patients with ESKD

Author/study	Cohort	Follow-up	Main results
Gill et al. [8]	4741 with graft failure, returning to dialysis	15 ± 11 months	Four per cent higher mortality risk after return to dialysis for each 1 mL/min/1.73 m2 higher eGFR at the time of dialysis initiation (HR 1.04; P < 0.01)
Molnar et al. [30]	747 with graft failure, returning to dialysis	1185 days	In an unadjusted model, each 1 mL/min/1.73 m2 higher eGFR at dialysis reinitiation was associated with a 6% higher risk of death (HR 1.06; P = 0.02); in adjusted models, this finding was not significant (HR 1.02; P = 0.54)