Table 2.
Baseline analytical values
| Serum biochemistry | n | Total | Non-AKI | AKI | P-value |
|---|---|---|---|---|---|
| sCr (mg/dL) | 38 350 | 0.80 (0.60–1.00) | 0.80 (0.60–1.00) | 0.93 (0.70–1.30) | <0.0001 |
| eGFR (mL/min/1.73 m2) | 38 350 | 91.33 (72.23–116.42) | 92.15 (73.10–117.11) | 72.40 (50.36–99.89) | <0.0001 |
| Uric acid (mg/dL) | 26 541 | 5.10 (4.00–6.50) | 5.10 (3.90–6.40) | 6.00 (4.60–7.50) | <0.0001 |
| Albumin (g/dL) | 32 952 | 4.00 (3.70–4.30) | 4.10 (3.70–4.30) | 3.80 (3.40–4.10) | <0.0001 |
| Calcium (mg/dL) | 27 891 | 9.00 (8.50–9.30) | 9.00 (8.50–9.30) | 8.70 (8.20–9.20) | <0.0001 |
| Ionic calcium (mg/dL) | 6018 | 4.46 (4.29–4.65) | 4.46 (4.29–4.65) | 4.45 (4.21–4.65) | 0.13 |
| Phosphate (mg/dL) | 24 272 | 3.40 (3.00–3.80) | 3.40 (3.00–3.80) | 3.40 (2.90–3.80) | 0.78 |
| Alkaline phosphatase (UI/l) | 26 346 | 76.50 (61.00–99.00) | 76.00 (60.00–99.00) | 80.00 (64.00–108.00) | <0.0001 |
| Glucose (mg/dL) | 45 629 | 98.00 (87.00–120.00) | 98.00 (86.00–119.00) | 111.00 (93.00–144.00) | <0.0001 |
| HbA1c (%) | 9022 | 6.00 (5.50–6.80) | 6.00 (5.50–6.80) | 6.30 (5.70–7.30) | <0.0001 |
| LDH (UI/l) | 26 767 | 371.00 (371.00–452.00) | 368.00 (316.00–449.00) | 410.00 (342.00–517.00) | <0.0001 |
| CRP (mg/dL) | 26 040 | 2.40 (0.90–6.30) | 2.30 (0.90–6.30) | 3.00 (1.30–7.10) | <0.0001 |
| Total proteins (g/dL) | 26 225 | 6.60 (6.10–7.10) | 6.60 (6.10–7.10) | 6.40 (5.90–6.90) | <0.0001 |
| Sodium (mEq/l) | 43 690 | 139.00 (137.00–141.00) | 139.00 (137.00–141.00) | 138.00 (136.00–141.00) | <0.0001 |
| Potassium (mEq/l) | 34 882 | 4.10 (3.80–4.40) | 4.10 (3.80–4.40) | 4.20 (3.80–4.60) | <0.0001 |
| CO2 (mEq/l) | 1795 | 29.00 (26.00–31.00) | 29.00 (26.00–31.00) | 28.00 (25.00–31.00) | 0.0448 |
| Urea (mg/dL) | 38 355 | 36.00 (27.00–49.00) | 36.00 (27.00–48.00) | 48.00 (35.00–68.00) | <0.0001 |
| Haematology | |||||
| Haemoglobin (g/dL) | 46 405 | 12.90 (11.60–14.20) | 13.00 (11.60–14.20) | 12.20 (10.70–13.50) | <0.0001 |
| Leucocytes (per µL) | 46 398 | 7.94 (6.19–10.35) | 7.90 (6.18–10.28) | 8.62 (6.42–11.74) | <0.0001 |
| Urinary biochemistry | |||||
| Density | 29 803 | 1.010 (1.010–1.020) | 1.010 (1.010–1.020) | 1.010 (1.010–1.020) | <0.0001 |
| Creatinine (mg/dL) | 11 002 | 74.00 (50.00–112.00) | 74.00 (50.00–113.00) | 69.00 (48.00–96.00) | <0.0001 |
| Albumin (mg/l) | 8998 | 7.90 (3.30–32.40) | 7.50 (3.20–29.60) | 17.80 (4.60–89.90) | <0.0001 |
| Sodium (mEq/l) | 3212 | 62.00 (35.00–92.00) | 62.00 (35.00–92.00) | 61.00 (39.00–89.00) | <0.0001 |
| UACR (mg/g) | 8999 | 10.00 (3.97–40.35) | 9.32 (3.85–35.17) | 24.74 (6.81–148.00) | <0.0001 |
| UPCR (mg/g) | 4669 | 87.20 (52.10–251.30) | 83.30 (51.10–210.10) | 169.60 (70.02–751.83) | <0.0001 |
Values expressed as median (IQR 25–75%).
IQR, interquartile range; sCr, serum creatinine; eGFR (mL/min/1.72 m2) assessed by the MDRD-4 equation; HbA1c, glycated haemoglobin; LDH, lactate dehydrogenase; CRP, C-reactive protein; UACR, urinary albumin:creatinine ratio; UPCR: urinary protein:creatinine ratio.