Genotype/ allele frequency |
Total women |
Normolipidemic women |
Hyperlipidemic women |
|
With CVD n = 265 |
Without CVD n = 258 |
With CVD n = 99 |
Without CVD n = 142 |
With CVD n = 166 |
Without CVD n = 116 |
GG |
49.4 |
43.8 |
43.5 |
45.8 |
53.0 |
41.4 |
GT |
30.2 |
53.5 |
32.3 |
51.4 |
29.0 |
56.0 |
TT |
20.4 |
2.7 |
24.2 |
2.8 |
18.0 |
2.6 |
|
p = 0.001* |
p = 0.001* |
p = 0.001* |
G |
64.5 |
70.5 |
59.6 |
71.5 |
67.5 |
69.4 |
T |
35.5 |
29.5 |
40.4 |
28.5 |
32.5 |
30.6 |
|
p = 0.041* OR = 1.31 (1.01–1.70) |
p = 0.008* OR = 1.69 (1.15–2.49) |
p = 0.695 OR = 1.09 (0.76–1.57) |
GT+TT Dominant model (GT+TT vs GG) |
50.6 56.2 p = 0.228 OR = 0.79 (0.56–1.12) |
56.5 54.2 p = 0.819 OR = 1.09 (0.65–1.84) |
47.0 58.6 p = 0.071 OR = 0.62 (0.38–1.01) |
GT+GG Recessive model (TT vs GT+GG) |
79.6 97.3 p = 0.001* OR = 9.17 (4.08–20.59) |
75.8 97.2 p = 0.001* OR = 11.04 (3.69–33.01) |
82.0 97.4 p = 0.001* OR = 8.30 (2.47–27.9) |
GG+TT Co-dominant model (GT vs GG+TT) |
69.8 46.5 p = 0.001* OR = 0.37 (0.26–0.53) |
67.7 48.6 p = 0.005* OR = 0.45 (0.26–0.77) |
71.0 44.0 p = 0.001* OR = 0.31 (0.19–0.52)* |