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. 2021 Jan 26;40(1):49-59. doi: 10.5937/jomb0-24704

Table 2. Genotype and allele frequency distribution of AdipoQ (rs1501299) polymorphism in women with and without CVD.

*p<0.05 is statistically significant

Genotype/ allele frequency Total women Normolipidemic women Hyperlipidemic women
With CVD n = 265 Without CVD n = 258 With CVD n = 99 Without CVD n = 142 With CVD n = 166 Without CVD n = 116
GG 49.4 43.8 43.5 45.8 53.0 41.4
GT 30.2 53.5 32.3 51.4 29.0 56.0
TT 20.4 2.7 24.2 2.8 18.0 2.6
p = 0.001* p = 0.001* p = 0.001*
G 64.5 70.5 59.6 71.5 67.5 69.4
T 35.5 29.5 40.4 28.5 32.5 30.6
p = 0.041* OR = 1.31 (1.01–1.70) p = 0.008* OR = 1.69 (1.15–2.49) p = 0.695 OR = 1.09 (0.76–1.57)
GT+TT Dominant model (GT+TT vs GG) 50.6 56.2 p = 0.228 OR = 0.79 (0.56–1.12) 56.5 54.2 p = 0.819 OR = 1.09 (0.65–1.84) 47.0 58.6 p = 0.071 OR = 0.62 (0.38–1.01)
GT+GG Recessive model (TT vs GT+GG) 79.6 97.3 p = 0.001* OR = 9.17 (4.08–20.59) 75.8 97.2 p = 0.001* OR = 11.04 (3.69–33.01) 82.0 97.4 p = 0.001* OR = 8.30 (2.47–27.9)
GG+TT Co-dominant model (GT vs GG+TT) 69.8 46.5 p = 0.001* OR = 0.37 (0.26–0.53) 67.7 48.6 p = 0.005* OR = 0.45 (0.26–0.77) 71.0 44.0 p = 0.001* OR = 0.31 (0.19–0.52)*