Table 1.
Treatment | Morris water maze | Elevated plus maze | Total proteins (mg/g tissue) | MDA (nM released/mg protein) | GSH (μM/mg tissue) | SOD (U/mg protein) | CAT (U/mg protein) | AchE (nM/mg protein) | |
---|---|---|---|---|---|---|---|---|---|
Escape latency (sec) | 1st retention (sec) | 2nd retention (sec) | |||||||
Control (vehicle) | 33.17 ± 1.30bc | 35.17 ± 1.38bc | 15.67 ± 0.67∗bc | 72.76 ± 1.78bcd | 45.57 ± 2.07b | 309.56 ± 6.69bc | 0.58 ± 0.04bcd | 42.72 ± 1.76b | 3.82 ± 0.09bcd |
Untreated control (AlCl3) | 63.00 ± 1.59acd | 64.17 ± 3.89acd | 59.83 ± 2.65acd | 35.37 ± 0.81acd | 97.33 ± 2.50acd | 103.91 ± 5.09acd | 0.89 ± 0.02acd | 28.66 ± 3.11ad | 0.34 ± 0.05acd |
AlCl3+TE+EO-25 | 45.00 ± 2.38ab | 52.00 ± 0.86abd | 33.00 ± 0.97∗abd | 58.17 ± 2.48ab | 56.23 ± 3.64b | 246.93 ± 10.96abd | 0.77 ± 0.03ab | 37.63 ± 3.57 | 1.95 ± 0.13abd |
AlCl3+TE+EO-50 | 38.17 ± 1.92b | 35.33 ± 0.76bc | 19.67 ± 0.67∗bc | 60.61 ± 1.80ab | 54.72 ± 2.98b | 287.39 ± 5.65bc | 0.69 ± 0.02ab | 41.92 ± 1.92b | 2.83 ± 0.22abc |
Values are expressed as the mean ± standard error of the mean. ap < 0.05 compared with the control. bp < 0.05 compared with untreated control (AlCl3). cp < 0.05 compared with the AlCl3+TE+EO-treated group (25 mg/kg); dp < 0.05 compared with the AlCl3+TE+EO-treated group (50 mg/kg). ∗p < 0.05 comparing second retention with first retention by paired t-test. AlCl3: aluminum chloride; TE+EO: turmeric extract and essential oil combination.