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. 2021 Jan 26;2021:6645720. doi: 10.1155/2021/6645720

Table 1.

Impact of turmeric extract and essential oil combination on cognitive performance and biochemical parameters in aluminum chloride-treated mice.

Treatment Morris water maze Elevated plus maze Total proteins (mg/g tissue) MDA (nM released/mg protein) GSH (μM/mg tissue) SOD (U/mg protein) CAT (U/mg protein) AchE (nM/mg protein)
Escape latency (sec) 1st retention (sec) 2nd retention (sec)
Control (vehicle) 33.17 ± 1.30bc 35.17 ± 1.38bc 15.67 ± 0.67bc 72.76 ± 1.78bcd 45.57 ± 2.07b 309.56 ± 6.69bc 0.58 ± 0.04bcd 42.72 ± 1.76b 3.82 ± 0.09bcd
Untreated control (AlCl3) 63.00 ± 1.59acd 64.17 ± 3.89acd 59.83 ± 2.65acd 35.37 ± 0.81acd 97.33 ± 2.50acd 103.91 ± 5.09acd 0.89 ± 0.02acd 28.66 ± 3.11ad 0.34 ± 0.05acd
AlCl3+TE+EO-25 45.00 ± 2.38ab 52.00 ± 0.86abd 33.00 ± 0.97abd 58.17 ± 2.48ab 56.23 ± 3.64b 246.93 ± 10.96abd 0.77 ± 0.03ab 37.63 ± 3.57 1.95 ± 0.13abd
AlCl3+TE+EO-50 38.17 ± 1.92b 35.33 ± 0.76bc 19.67 ± 0.67bc 60.61 ± 1.80ab 54.72 ± 2.98b 287.39 ± 5.65bc 0.69 ± 0.02ab 41.92 ± 1.92b 2.83 ± 0.22abc

Values are expressed as the mean ± standard error of the mean. ap < 0.05 compared with the control. bp < 0.05 compared with untreated control (AlCl3). cp < 0.05 compared with the AlCl3+TE+EO-treated group (25 mg/kg); dp < 0.05 compared with the AlCl3+TE+EO-treated group (50 mg/kg). p < 0.05 comparing second retention with first retention by paired t-test. AlCl3: aluminum chloride; TE+EO: turmeric extract and essential oil combination.