Figure 3.

(a,b) The box plots show the tear glucose concentrations in the five groups with occult blood testing. Open circles stand for outliers that are >1.5 and ≤3 box lengths above the 75% tile, and stars stand for outliers that are >3 box lengths above the 75% tile. (a) Participants without diabetes (occult blood −, +, ++, +++; n = 112, 17, 29, 7,15, respectively). (b) Participants with diabetes (occult blood −, +, ++, +++; n = 192, 46, 79, 33, 10, respectively). (c–f) Comparison of the plasma and tear glucose concentrations between participants without diabetes (open columns) and participants with diabetes (closed columns). Data are expressed as the mean ± standard error of the mean. (c) Preprandial plasma glucose concentrations at 12 and 18 o’clock on the day of admission (samples collected from participants without diabetes, n = 22; samples collected from participants with diabetes, n = 47). (d) Preprandial tear glucose concentrations at 12 and 18 o’clock on the day of admission (samples collected from participants without diabetes, n = 22; samples collected from participants with diabetes, n = 47). (e) The 2‐h postprandial plasma glucose concentrations at 14 and 20 o’clock on the day of admission (samples collected from participants without diabetes, n = 28; samples collected from participants with diabetes, n = 41). (f) The 2‐h postprandial plasma glucose concentrations at 14 and 20 o’clock on the day of admission (samples collected from participants without diabetes, n = 28; samples collected from participants with diabetes, n = 41). *P < 0.05, **P < 0.001. (g–j) Plasma (open circles) and tear (closed circles) glucose dynamics (samples collected from participants without diabetes, n = 7–18; samples collected from participants with diabetes, n = 19–24). Data are expressed as the mean ± standard error of the mean. Data are expressed as the mean ± standard error of the mean. (g) Participants without diabetes on the day of admission. (h) Participants with diabetes on the day of admission. (i) Participants without diabetes on day 2 of admission. (j) Participants with diabetes on day 2 of admission. AD, after dinner; AL, after lunch; BB, before bedtime; BD, before dinner; BL, before lunch.