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. 2020 Dec 29;15(2):623–641. doi: 10.1002/1878-0261.12840

Fig 8.

Fig 8

Schematic summary of circ102049 as a metastasis‐promoting ncRNA in CRC. Circ102049 promoted CRC development and progression via a miR‐761/miR‐192‐3p‐FRAS1‐dependent mechanism. Notably, due to the abnormal distribution of DGCR8 protein, circ102049 may also reduce the mature products of miR‐761 and miR‐192‐3p in cytoplasm indirectly.