Two-dimensional trajectory of the coefficients αP, αN, and β2 during training mapped in the Tversky coefficients space αP,tversky = 2 αP/(1 + β2) and . In this representation, using the Dice loss corresponding to operating at a fixed point (1,1), using the Effectiveness loss corresponding to operating at a fixed point on the gray line αP,tversky + αN,tversky = 2, and using the Tversky loss corresponding operating at a fixed point anywhere in the plane defined by αP,tversky ≥ 0 and αN,tversky ≥ 0. With the adaptive training methodology, the parameters are updated at every iteration step leading to a dynamic trajectory as the optimization is carried out (colormap correspond to iteration number).