Figure 4.

Construction and evaluation of nomogram prognosis model in TCGA cohort. (A) Nomogram based on m⁶A risk score and clinicopathologic factors for 1-, 3-, and 5-year overall survival prediction of ccRCC patients. (B) Evolution of prognostic nomogram model for 1-, 3-, and 5-year overall survival prediction. (C) Decision curve analysis compared overall survival benefits among nomogram, tumor stage, tumor grade, and m⁶A risk score. Black line: all victims dead. Gray line: none victims dead. (D) Time-dependent ROC curve of 1-, 3-, and 5-year overall survival prediction for prognostic nomogram model. m⁶A, N⁶-methyladenosine; TCGA, The Cancer Genome Atlas; ccRCC, clear-cell renal cell carcinoma; ROC, receiver operating characteristic.