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. 2021 Jan 21;11:606227. doi: 10.3389/fphar.2020.606227

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Copyright © 2021 Lu, Ji, Luo, Lan, Han, Chen, Liu, Lin, Lu, Wu Guo and Zou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of emodin-NP (A) FTIR spectra showing amide bands I and II of the copolymer at 1757 and 3443 cm⁻¹, respectively (B) ¹H NMR spectrum with characteristic proton peaks of PEG and PLA at 3.65 and 5.2 ppm, respectively (C) size distribution spectrum (D) zeta potential of mPEG-PLA-CS-MBI determined by laser diffraction (E) morphology of mPEG-PLA-CS-MBI nanoparticles determined by TEM (F) in vitro release of MBI from mPEG-PLA-CS-MBI in pH 7.2 PBS at 37°C.