Table 1.

a. Effect of ngr1 gene deletion on the clinical course in MOG_35-55 EAE. b. Effect of ngr1 gene deletion on the clinical course in rMOG EAE.

	ngr1+/+	ngr1−/−	p value
a
Incidence	76/99	32/60
Mean day of disease onset (dDO)	13.5 ± 0.3	16.1 ± 0.6	0.012
Mean maximal score (MMS)	3.2 ± 0.2	2.3 ± 0.1	0.018
Area under the curve (AUC)	39.2 ± 3.1	22.2 ± 2.3	0.001
Mortality rate	3/99	2/60
b
Incidence	21/22	10/12
Mean day of disease onset (dDO)	14.1 ± 0.4	20.6 ± 0.9	0.008
Mean maximal score (MMS)	2.9 ± 0.2	2.1 ± 0.2	0.022
Area under the curve (AUC)	33.9 ± 2.5	15.3 ± 1.7	0.001
Mortality rate	1/22	1/12

^aDisease parameters of the respective EAE clinical course in ngr1^+/+ and ngr1^−/− mice, as shown in Fig. 1a. Data represent mean ± SEM.

^bDisease parameters of the respective EAE clinical course in ngr1^+/+ and ngr1^−/− mice, as shown in Supplementary Fig. 1a. Data represent mean ± SEM.