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. 2021 Feb 3;11:2933. doi: 10.1038/s41598-021-82492-x

Table 1.

Demographic and epidemiology of the study patients.

Characteristics Patients (N = 659) ARDS patients (N = 76) Non-ARDS patients (N = 583) P value
Demography
Age
 Median(IQR)- years 50.0 (37.0–62.0) 56.5(47.5–67.8) 49.0(36.0–60.0) 0.000
 Distribution—no./total no. (%) 0.000
 14–30 years 70/659(10.6%) 2/76(2.6%) 68/583(11.7%)
 30–70 years 545/659(82.7%) 61/76(80.3%) 484/583(83%)
  ≥ 70 years 44/659(6.7%) 13/76(17.1%) 31/583(5.3%)
Gender 0.000
 Male—no./total no. (%) 332/659(50.4%) 58/76(76.3%) 274/583(47.0%)
 Female—no./total no. (%) 327/659(49.6%) 18/76(23.7%) 309/583(53.0%)
BMI
 Median(IQR) 23.9(21.5–25.9) 25.5(21.5–25.7) 23.7(23.2–27.7) 0.001
 Distribution—no./total no. (%) 0.007
  < 23 229/591(38.7%) 14/65(21.5%) 215/526(40.9%)
 23–25 161/591(27.2%) 17/65(26.2%) 144/526(27.4%)
  > 25 201/591(34.1%) 34/65(52.3%) 167/526(31.7%)
Medical staff—no./total no. (%) 9/659(1.4%) 1/76(1.3%) 8/583(1.4%) 0.968
Pregnancy history—no./total no. (%) 11/659(1.67%) 3/76(3.9%) 8/583(1.4%) 0.123
Smoking history—no./total no. (%) 51/654(7.8%) 11/76(14.5%) 40/578(6.9%) 0.198
Epidemiology—no./total no. (%)
History of exposure 447/630(70.9%) 38/70(54.3%) 409/560(73.0%) 0.002
Family members have disease 258/583(44.3%) 27/76(35.5%) 231/507(45.6%) 0.285
Number of cases in family members—Median(IQR) 1(0–13) 1(0–1) 1(0–1) 0.263
Have been to Wuhan 381/657(57.9%) 34/76(44.7%) 347/581(59.7%) 0.091
Stay in ICU 33/608(5.4%) 33/73(45.2%) 0/535(0%) 0.000
Interval between date of contact and date of onset—Median (IQR) 5(3–9) 6(3–8) 5(3–10) 0.901
The interval between the onset date and the visit date
 Median (IQR) 2(0–5) 3(1–6) 1(0–4) 0.772
 Distribution—no./total no. (%) 0.035
  ≤ 2 days 385/651(59.1%) 34/75(45.3%) 351/576(60.9%)
 3–5 days 142/651(21.8%) 22/75(29.3%) 120/576(20.8%)
  > 5 days 124/651(19.0%) 19/75(25.3%) 105/576(18.3%)
The interval between the date of onset and the date of admission
 Median (IQR) 5(2–10) 6(3–8) 5(3–8) 0.759
 Distribution—no./total no. (%) 0.250
  ≤ 2 days 182/656(27.7%) 15/76(19.7%) 167/580(28.8%)
 3–5 days 167/656(25.5%) 22/76(28.9%) 145/580(25.0%)
  > 5 days 307/656(46.8%) 39/76(51.3%) 268/580(46.2%)
The interval between the onset date and the antiviral date
 Median (IQR) 5(3–10) 4(4–9) 5(4–9) 0.278
 Distribution—no./total no. (%) 0.250
  ≤ 2 days 182/656(27.7%) 15/76(19.7%) 167/580(28.8%)
 3–5 days 167/656(25.5%) 22/76(28.9%) 145/580(25.0%)
  > 5 days 307/656(46.8%) 39/76(51.4%) 268/580(46.2%)

BMI, body mass index; ICU, intensive care unit; no., number.

Data are presented as medians (interquartile ranges, IQR) and no./total no. (%).