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. 2021 Feb 3;11:2961. doi: 10.1038/s41598-021-82483-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Co-localisation of mercury by AMG and LA-ICP-MS. (a) Black AMG staining is present in two regions of the adrenal medulla (MED), but not in the adjacent adrenal cortex (COR), or in a large blood vessel (BV). AMG and hematoxylin. (b) An enlargement of the area within the box in (a) shows numerous chromaffin cells containing black AMG grains. (c) LA-ICP-MS of an adjacent section shows mercury in the two adrenal medulla regions, but not in the cortex or blood vessel. All images from a 98 year-old male. Scale = counts per second (proportional to abundance).