Table 1.

Relative distribution of aminopeptidase activity in the P. falciparum cellular fractions (C1, C2, V1 and V2) calculated from a standard curve prepared using free NMMec.

Fraction	H-Arg-NHMec		H-Leu-NHMec
	Enzyme activity (Unitsa)	Relative activity (%)	Enzyme activity (Unitsa)	Relative activity (%)
Total	178 ± 15.6	100	133.6 ± 1.1	100
Cytosolic 1 (C1)	145.5 ± 19.6	80 ± 7.5	116.4 ± 17.3	85 ± 10.5
Cytosolic 2 (C2)	13 ± 9.3	6.8 ± 4.3	8.4 ± 7.9	5.8 ± 4.9
Vacuolar 1 (V1)	17.5 ± 12.6	9.4 ± 6.7	11.3 ± 8.7	8.3 ± 6.9
Vacuolar 2 (V2)	6.4 ± 5.2	3.8 ± 3.3	1.3 ± 1.5	1.1 ± 1.2

^aOne unit of enzyme is defined as the nanomoles of NHMec released per 30 min at 37 °C.