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. 2021 Jan 21;10:553628. doi: 10.3389/fonc.2020.553628

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Copyright © 2021 Dong, Lv, Gu, Zhang and Ye

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LAGE3 affected the migration and invasion of TNBC cell lines via EMT pathways. (A–D) The number of migrated or invaded cells in different groups as determined Transwell (scale bar = 200 μm). (E) The of EMT-related proteins in si-NC or si-LAGE3 cells as determined by Western blotting assay. All experiments were repeated at least three times. Group data were compared with unpaired Student’s t-test (two-tailed). EMT, epithelial–mesenchymal transition. **p < 0.01; ***p < 0.001; ****p < 0.0001.