Why carry out this study?

To determine the demographic and clinical characteristics of patients treated with apremilast in the Corrona Psoriasis Registry.

What was learned from the study?

In this observational study of apremilast users enrolled in the Corrona Psoriasis Registry, most had less-severe skin disease and greater biologic experience versus trials in patients with moderate-to-severe psoriasis. One-third of patients had a Psoriasis Epidemiology Screening Tool score indicating PsA, and many received concomitant biologics.

In real-world clinical practice, physicians prescribed apremilast to patients who had less-severe psoriasis compared with apremilast patients in the phase 3 ESTEEM studies, but apremilast patients in the Corrona Psoriasis Registry had psoriasis severity that was more comparable to patients in the phase 4 UNVEIL study.