Table 3.
ALE results for studies using different measures of rsFC to study the effect of ECT in depression.
| Analysis | ECT | FDR/ FWER | Brain region | Cluster size (mm3) | Peak MNI Coordinates (x, y, z) | ALE value | Z score | P |
|---|---|---|---|---|---|---|---|---|
| ALFF voxel wise | Pre > post | FWER* | L. CG, BA 32 | 584 | −8, 24, 32 | 0.011 | 4.715 | <0.0001 |
| ALFF voxel wise | Post > pre | FWER* | No significant clusters found | |||||
| ReHo voxel cluster | Pre > post | FWER* | No significant clusters found | |||||
| Network Based | Post > pre | FDR | L. PCC, BA 31 R. PCC, BA 31 | 600 | 2, −56,32 8, −56, 24 | 0.014 0.013 |
5.378 5.165 |
<0.001 <0.001 |
| fALFF voxel to voxel | Pre > post | FWER | No significant clusters found | |||||
| Seed (R. HC) to voxel | Post > pre | FWER* | R. HC and R. PHG | 8864 | 42, −22, −11 | 0.008 | 4.296 | <0.0001 |
| Seed (R. HC) to voxel | Post > pre | FDR | No significant clusters found | |||||
| Seed (R. HC) to voxel | Pre > post | FDR | No significant clusters found | |||||
| Seed (dmPFC) to voxel | Post > pre | FWER* | No significant clusters found | |||||
| Seed (L. anterior Insula (ventral) to voxel | Post > pre | FWER# | No significant clusters found | |||||
*
Cluster level FWER;
#
Voxel level FWER.
pre> post, Greater before the ECT course; post> pre, Greater after the ECT course/specified number of ECT sessions.