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. 2021 Jan 21;11:589125. doi: 10.3389/fneur.2020.589125

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Copyright © 2021 Jin, Yang, Zhang, Wang, Liu, Yang, Long, Li, Gong and Lai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Images showing areas of reduced thalamic functional connectivity in subjects with orofacial pain compared with that of the control group. Subjects with orofacial pain exhibited significantly lower functional connectivity (yellow) in clusters located in the left cerebellum, bilateral anterior cingulate cortices, right parahippocampal gyrus, bilateral middle frontal gyri, right inferior frontal gyrus, bilateral superior frontal gyri, right middle temporal gyrus, right insula, and the left thalamus (p < 0.05, family-wise error corrected, voxel > 100). At right, color bars indicate t-values.