Fig. 6.

Methylation status of DNA damage repair genes correlated with TERF1 in breast cancer. UCSC Xena browser was used to analyze the DNA methylation of PARP1, XRCC5 and PRKDC correlated with TERF1 in breast cancer subtypes. DNA methylation of these genes was found to be distinctly different in the case of basal-like subtype in comparison to otherwise pattern. Red and blue arrows define hypermethylation and hypomethylation consequently. TERF1, telomeric repeat-binding factor 1; PARP1, Poly [ADP-ribose] polymerase 1; XRCC5, Ku80; PRKDC, Protein Kinase DNA Activated Catalytic subunit. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)