Table 1.
Datasets of the shelterin complex genes in breast cancer (Kaplan-Meier plotter).
| Gene | Affymetrix ID | No. of cases | Cut off value | HR | 95% CI | P-Value |
|---|---|---|---|---|---|---|
| TERF-1 | 203448_s_at | 3951 | 700 | 1.16 | 1.04–1.3 | 0.0062 |
| TERF-2 | 1555185_x_at | 1764 | 44 | 1.16 | 1–1.36 | 0.056 |
| Rap1/TERF2IP | 201174_s_at | 3951 | 1339 | 1.03 | 0.93–1.15 | 0.56 |
| POT1 | 204353_s_at | 3951 | 422 | 0.85 | 0.76–0.94 | 0.0027 |
| ACD/TPP1 | 204617_s_at | 3951 | 414 | 1.06 | 0.95–1.18 | 0.30 |
| TIN2 | 220052_s_at | 3951 | 585 | 0.83 | 0.74–0.92 | 0.0006 |
Abbreviations: HR, hazard ratio; CI, confidence level; TERF1, telomeric repeat-binding factor 1; TERF2, telomeric repeat-binding factor 2; Rap1/TERF2IP, telomeric-repeating binding factor 2-interacting factor; POT1, protection of telomeres protein 1; TPP1/ACD; Adrenocortical dysplasia protein; TIN2/TINF2, TERF1-interacting nuclear factor 2.