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Sema3E promoted vascular regeneration. (A) Representative photomicrographs from isolectin B4-stained retinal flatmounts from normoxic or P17 OIR mice treated intravitreally with vehicle (PBS) or recombinant Sema3E (rSema3E). Scale bar 500 μm. Histograms representing VO (B) and NV areas (C) that were significantly reduced in rSema3E-treated retinas in contrast to vehicle-treated (**p < 0.01 vs vehicle, values are mean ± SEM, n = 4–5 retinas).
