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. 2021 Jan 21;9:624871. doi: 10.3389/fcell.2021.624871

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Copyright © 2021 Sumei, Xiangyun, Fenrong, Xueguang, Sijun, Bin, Xiaolei, Yongjiu, Kaichun, Qingchuan, Yongzhan and Bin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DHRS3 induced cell-cycle arrest in G1 phase and cell apoptosis. (A) Analysis of the cell cycle was performed by flow cytometry in the MKN28 cells stably transfected with DHRS3 or empty vector. Overexpression of DHRS3 resulted in an increase in the percentage of cells in G1 phase (57.21 vs. 46.13% in control cells). (B) The rate of cell apoptosis was determined by flow cytometry. Q4 indicates early apoptotic cells, Q2 shows late apoptotic cells. Results were obtained from four independent experiments.