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. 2021 Jan 21;8:613621. doi: 10.3389/fbioe.2020.613621

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Copyright © 2021 Hagen, Lehmann, Aurich, Bauer, Melzer, Moellerberndt, Patané, Schnabel and Burk.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A,B) Platelet (PLT; A) and white blood cell (WBC; B) counts at the different stages of blood processing; values for whole blood, plasma, and concentrate were obtained using three technical replicates (blood bags), for each horse; values for concentrate pooled and lysate were obtained after all bags from one animal had been pooled; Friedman and Wilcoxon tests for group comparisons were performed for the former (p-values are indicated); bars represent the median values, error bars the 95% confidence intervals. (C–E) PLT (C) and WBC (D) counts in whole blood vs. concentrate, and WBC vs. PLT recovery rates (E) (p < 0.05, based on Spearman's rank correlation). All data were obtained from n = 19 horses.