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. 2021 Feb 3;12:757. doi: 10.1038/s41467-021-21026-5

Fig. 1. Mutational landscape of skull-base chordoma (n = 80).

Fig. 1

a The recurrence status (no: gray; yes: red), age (from younger to older: blue to yellow), and sex (female: red; male: blue); b the proportions of somatic single-base substitutions (SBS) found in each chordoma patient that can be attributed to COSMIC SBS signatures; c the proportions of somatic double-base substitutions (DBS) found in each chordoma patient that can be attributed to COSMIC DBS signatures; d number of single nucleotide variants (SNVs) identified in each chordoma sample; e the de novo signature A, which is not mapped to any of COSMIC indel signatures; f the proportions of de novo indels found in each chordoma patient; g number of indels found in each chordoma sample; h number of structural variants (SVs) found in each chordoma sample. See also Supplementary Figs. 4 and 5 and Tables 2 and 3.