Table 2.
Baseline characteristics of epilepsy and comparison cohorts in the CPRD and SAIL databank.
| CPRD | SAIL | |||
|---|---|---|---|---|
| Baseline characteristic |
Epilepsy cohort (n = 9,871) |
Comparison cohort (n = 185,800) |
Epilepsy cohort (n = 5,569) |
Comparison cohort (n = 110,021) |
| Male | 5,062 (51·3%) | 95,647 (51.5%) | 2,874 (51.6%) | 56,729 (51.6%) |
| Median age on entry (IQR) | 57 (39–73) | 58 (40–74) | 54 (37–70) | 54 (37–70) |
| Level of deprivationa | ||||
| 1 (least deprived) | 1,908 (19.3%) | 40,105 (21.5%) | 905 (16.3%) | 21,022 (19.1%) |
| 2 | 2,190 (22.2%) | 43,077 (23.2%) | 928 (16.7%) | 20,186 (18.4%) |
| 3 | 1,870 (18.9%) | 37,066 (20.0%) | 1,248 (22.4%) | 24,158 (22.0%) |
| 4 | 1,959 (19.9%) | 35,257 (19.0%) | 1,204 (21.6%) | 22,714 (20.7%) |
| 5 (most deprived) | 1,937 (19.6%) | 30,111 (16.2%) | 1,280 (23.0%) | 21,776 (19.8%) |
| missing | 7 (0.1%) | 184 (0.1%) | <5 (0.1%) | 165 (0.2%) |
| Follow up | ||||
| Median follow-up time (years) | 3.2 (1.2–6.6) | 4.3 (1.9–7.7) | 4.7 (IQR 1.8–8.6) | 5.9 (IQR 2.6–9.7) |
| Alcohol consumptionb,c | ||||
| Non-drinker | 1,774 (18.0%) | 26,360 (14.2%) | ||
| Former drinker | 315 (3.2%) | 2,772 (1.5%) | ||
| Occasional drinker | 1,248 (12.6%) | 24,087 (13.0%) | ||
| Moderate drinker | 3,359 (34.0%) | 74,782 (40.3%) | ||
| Heavy drinker | 958 (9.7%) | 11,881 (6.4%) | ||
| Missing | 2,217 (22.5%) | 45,968 (24.6%) | ||
Data on alcohol consumption could only be calculated in the CPRD.
a
Based-on quintiles of multiple deprivation where 1 is the most deprived and 5 is the least deprived.
b
Alcohol consumption status estimated at index date based on algorithm by Parisi et al. (17).
c
P < 0.001. The black shaded portion represents that the descriptive analysis was not conducted in the SAIL Databank.