Table 2.
Patterns of recurrence of the wide-margin, narrow-margin, and positive-margin plus stereotactic body radiotherapy (SBRT) groups.
| Variable | Wide-margin group | Narrow-margin group | P-Value | Positive-margin plus SBRT |
|---|---|---|---|---|
| (N = 134) | (N = 106) | (Wide vs. Narrow) | (N = 9) | |
| Total recurrence | 59 (44.0%) | 69 (65.1%) | 0.001 | 2 (22.2%) |
| Type of recurrence | ||||
| Intrahepatic recurrence | 54 (40.3%) | 67 (63.2%) | 0.321 | 2 (22.2%) |
| Extrahepatic recurrence | 7 (5.2%) | 10 (9.4%) | 0.662 | 0 (0.0%) |
| Sites of intrahepatic recurrence | ||||
| Marginal recurrence | 6 (4.5%) | 22 (20.8%) | 0.003 | 0 (0.0%) |
| Intrahepatic single-nodule | 26 (19.4%) | 13 (12.3%) | 0.002 | 1 (11.1%) |
| Intrahepatic multiple-nodule | 16 (11.9%) | 34 (32.1%)* | 0.010 | 1 (11.1%) |
| Unclear | 6 (4.5%) | 5 (4.7%) | 0.556 | 0 (0.0%) |
| Time to recurrence | ||||
| Total recurrence | ||||
| ~ 3 months (include 3) | 11 (8.2%) | 16 (15.1%) | 0.530 | 0 (0.0%) |
| 3~6 months | 15 (11.2%) | 30 (28.3%) | 0.033 | 0 (0.0%) |
| 6~9 months | 20 (14.9%) | 41 (38.7%) | 0.004 | 2 (22.2%) |
| 9~12 months | 28 (20.9%) | 46 (43.4%) | 0.028 | 0 (0.0%) |
| Marginal recurrence | ||||
| ~ 3 months (include 3) | 7 (6.6%) | 0 (0.0%) | 0.022 | 0 (0.0%) |
| 3~6 months | 11 (10.4%) | 1 (0.7%) | 0.074 | 0 (0.0%) |
| 6~9 months | 13 (12.3%) | 3 (2.2%) | 0.164 | 0 (0.0%) |
| 9~12 months | 15 (14.2%) | 3 (2.2%) | 0.033 | 0 (0.0%) |
| Intrahepatic multiple-nodule | ||||
| ~ 3 months (include 3) | 10 (9.4%) | 4 (3.0%) | 0.252 | 0 (0.0%) |
| 3~6 months | 20 (18.9%) | 6 (4.5%) | 0.088 | 0 (0.0%) |
| 6~9 months | 25 (23.6%) | 7 (5.2%) | 0.057 | 1 (11.1%) |
| 9~12 months | 29 (27.4%) | 9 (6.7%) | 0.010 | 1 (11.1%) |
*8 of them with concurrent marginal recurrence. P < 0.05 was indicated by bold values.