Table II.

Whole exon sequencing results of patients with nasopharyngeal carcinoma.

Chromosome	Position (1-based)	Gene name	Original	Mutation	Original (peptide)	Mutation (peptide)	Annotation	P-valuea
chr10	135440216	FRG2B	G	A	H	Y	FSHD region gene 2 family member B	0.87870
chr10	17147521	CUBN	G	T	P	T	Cubilin	0.01335
chr1	12939765	PRAMEF4	A	G	L	P	PRAME family member 4	0.00000
chr12	31242081	DDX11	G	A	R	Q	DEAD/H-box helicase 11	0.27880
chr12	8327016	ZNF705A	T	C	A	T	zinc finger protein 705A	0.01544
chr15	102463117	OR4F4	T	G	H	P	Olfactory receptor family 4 subfamily F member 4	0.49690
chr15	28197037	OCA2	T	C	H	R	OCA2 melanosomaltrans-membrane protein	0.01397
chr15	45392075	DUOX2	G	A	S	L	Dual oxidase 2	0.21210
chr15	74374822	GOLGA6A	T	G	H	P	golgin A6 family member A	0.00665
chr16	48258198	ABCC11	C	T	G	R	ATP binding cassette subfamily C member 11	0.07139
chr17	76433898	DNAH17	T	C	H	R	Dyneinaxonemal heavy chain 17	0.20260
chr17	78178893	CARD14	C	T	R	W	Caspase recruitment domain family member 14	0.07064
chr2	21231524	APOB	G	A	P	L	Apolipoprotein B	0.30960
chr2	228135631	COL4A3	C	T	P	L	Collagen type IV alpha 3 chain	0.00149
chr2	87214281	RGPD1	T	G	V	G	RANBP2-like and GRIP domain containing 1	0.05126
chr3	172835082	SPATA16	C	T	G	E	Spermatogenesis associated 16	0.08735
chr3	37574951	ITGA9	G	A	G	E	Integrin subunit alpha 9	0.28760
chr4	120241902	FABP2	T	C	T	A	Fatty acid binding protein 2	0.03159
chr4	190881957	FRG1	G	T	D	Y	FSHD region gene 1	0.05745
chr9	33386465	AQP7	A	G	Y	H	Aquaporin 7	0.04698
chr9	42376286	ANKRD20A2	C	T	A	V	Ankyrin repeat domain 20 family member A2	0.08193

^aSingle nucleotide variations between upward and downward progressing types of nasopharyngeal carcinoma were detected by whole exome sequencing and Genome-Wide Association Studies were used to analyze differential gene expression. P<0.05 was considered as statistically significant.