Table 4.

Functions of m6A regulators in ncRNA metabolism.

ncRNA	Molecule	Cancer type	Biological function	Effect	Reference
miR221/222	METTL3	Bladder Cancer	Promote pri-miRNA processing	Positive	(126)
miR-1246	METTL3	Colorectal Carcinoma	Promote pri-miRNA processing	Positive	(127)
miR-143-3p	METTL3	Non-Small Cell Lung Cancer	Promote pre-miRNA processing	Positive	(128)
miR-29a	WTAP	Glioblastoma	Regulatory gene expression	Negative	(129)
miR-34-5p/miR-181-5p	IGF2BP1	Ovarian, Liver and Lung cancer	Maintain SRF target genes expression	Negative	(130)
miR-491-5p	IGF2BP1	Non-Small Cell Lung Cancer	Regulatory gene expression	Negative	(131)
miR-29A-3P, miR-29B-3P, miR-222, miR-1266-5P, miR-1268a, and miR-671-3p	HNRNPA2B1	Breast Carcinoma	Alter miRNAs transcriptome	Bidirectional	(132)
Linc00958 and miR3619-5p	METTL3	Hepatic Carcinoma	Stabilize lncRNA and enable the ceRNA model	Positive	(134)
lncRNA-NEAT1	ALKBH5	Gastric Carcinoma	Promote interaction	Positive	(103)
LINC01234	HNRNPA2B1	Non-Small Cell Lung Cancer	Promote interaction	Positive	(135)
lncRNA-DANCR	IGF2BP2	Pancreatic Carcinoma	Stabilize lncRNA	Positive	(136)
XIST	WTAP/RBM15/RBM15B	Gene silencing on the X chromosome	Promote XIST -mediated gene repression	Positive	(29, 138)
XIST	METTL14/YTHDF2	Colorectal Carcinoma	Mediate XIST degradation	Positive	(139)
circNSun2	YTHDC1	Colorectal Carcinoma	Promote cytoplasmic export of circRNAs	Positive	(140)
circRNAs	YTHDF2	Innate Immunity	Mediate circRNA degradation	Negative	(141)