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. 2021 Jan 21;8:618226. doi: 10.3389/fped.2020.618226

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Copyright © 2021 Zheng, Luo, Yang, Dong, Yu and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Increased YAP and ANKRD1 mRNA expression in an RRV-induced murine BA model. (A) RRV-induced BA model (age 2 weeks). Representative image of RRV-infected mice (left) and control (right). BA related symptoms, including reduced growth, jaundice, and oily fur were observed in RRV-infected mice. (B) Body weight of RRV-infected and control mice at different time points. Significant weight loss was observed in RRV-infected mice (n = 5). (C) Elevated expression of ANKRD1 and Yap mRNA in RRV-induced BA mouse livers (n = 5).