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. 2021 Jan 21;9:629796. doi: 10.3389/fcell.2021.629796

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Copyright © 2021 She, Fan, Wang, Li, Sun, Tang, Zhang, Wu, Zheng and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Therapeutic outcome after tracheal replacement. Bronchoscopy and gross examination images of the biomimetic trachea 4 weeks after the replacement surgery (A,B). Histological images of a transverse section of the biomimetic trachea showing a cartilage ring (C,C1–C4) and a PCL ring (D,D1–D4) 4 weeks after the replacement surgery. Bronchoscopy and gross examination images of the biomimetic trachea 8 weeks after the replacement surgery (E,F). Histological images of a transverse section of the biomimetic trachea showing a cartilage ring (G,G1–G4) and a PCL ring (H,H1–H4) 8 weeks after the replacement surgery. The biomimetic trachea is delineated by red dotted lines.