Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 21;9:626027. doi: 10.3389/fcell.2021.626027

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Lv, Liu, Zhang, Hu, Wu and Ren.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Downregulation of circCOL5A1 suppressed the growth of keloids and ECM deposition in vivo. (A) Images of subcutaneous keloid grafts in circCOL5A1 low expression group and control group. (B) The relative volume of keloid grafts was analyzed. (C) The weight of the keloid grafts was evaluated. (D) Representative images of HE staining of keloid nodules in different intervention groups (magnification, 100× and magnification, 200×). (E) The relative expression level of collagen I, collagen III, and α-SMA was observed in keloid grafts by IHC (magnification, 200× and magnification, 400×). (F) The protein levels of collagen I, collagen III, and α-SMA were evaluated in subcutaneous keloid grafts by western blot analysis. Data was shown as mean ± SD. ns indicated no significance, ^##P < 0.01, ^###P < 0.001, vs. si-NC.