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. 2021 Jan 21;11:503256. doi: 10.3389/fgene.2020.503256

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Copyright © 2021 Gao, Zhang, Chen, Li, Wang, Wen, Xie, Mai, Wang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional analysis of mRNA in the ceRNA network (ADAM19 and TGFBI). (A) Enriched TGF-β1 signaling pathway for TGFBI in the GSE116250 dataset. (B) Enriched TGF-β1 signaling pathway for TGFBI in the GSE97358 dataset. (C) Enriched TGF-β1 signaling pathway for ADAM19 in the GSE116250 dataset. (D) Inference Score for ADAM19. (E) Inference Score for TGFBI. (F) Inference Score for SMAD4. (G) Knockdown of expression of ADAM19 and TGFBI reduced expression of myofibroblast-associated genes. n = 3 per group. *P < 0.05, **P < 0.01, ***P < 0.001.